Endocrine Abstracts

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...

Introduction: Hemangiopericytomas (HPC) are rare vascular tumours that may be associated with hypoglycaemia. Here we report a case of HPC with multiple metastases, accompanying severe recurrent hypoglycaemia due to the combination of different aetiologies.Case report: A 21 year-old woman was hospitalised due to loss of consciousness. The patient has been diagnosed as HPC by tibia mass biopsy 1 year ago. Tumour embolization was made several times. On admi...

Introduction: Pregnancy or lactation related osteoporosis (PLO) is very rare. It usually occurs in the third trimester or in the early post partum period and manifestations are severe back pain and loss of height due to vertebral fractures. Its etiology is not well understood. Classical treatment is cessation of lactation, calcium and Vit-D supplementation and biphosphanates in chosen cases. All osteoporosis drugs are approved mainly for post-menouposal osteoporosis a...

Introduction: In this study, we aimed to evaluate the effects of fat distribution and some adipokines on insulin resistance (IR) in prediabetic patients.Materials and Methods: cases were divided into three groups according to 75 gr-oral glucose tolerance test (OGTT) results [27 cases impaired fasting glucose (IFG), 36 cases impaired glucose tolerance (IGT) and 24 healthy control subjects]. Serum fasting insulin levels and lipid parameters were measured. ...

ACC is a rare, heterogeneous malignancy with poor prognosis. Data from the German ACC Registry (n=478) indicate a 5-year survival rate of 47%. In addition to mitotane, cytotoxic drugs are standard of care in advanced ACC. The best results have been reported by Berruti et al. for the combination of mitotane with etoposide, doxorubicin and cisplatin with an objective tumor response rate of 49% in 72 patients. A response rate of 36% was published for the combination...

Objective: Tumor induced osteomalacia (TIO) belongs to the group of hypophosphatemic osteomalacias and is induced by a tumor. It is not common disease.Case report: We describe a 34-year-old caucasian man who presented with a 5 year history of diffuse bone pain and muscle weakness. Laboratory investigations showed normal calcium level, low phosphate level between 1.01 mg/dl, and 1.6 mg/dl (reference range: 2.6–5.5 mg/dl), raised alkaline phosphatase ...

Introduction: Parathyroid surgical therapy differs because the glands are small and of variable number and location. Although localization studies have improved greatly, we may not reliably determine the number and location of all diseased glands preoperatively. Ultrasonography (US) is the most widely used imaging method. In this study, we aimed to demonstrate how the surgical outcomes change when the surgeon accompanies the endocrinologist during preoperative ultrasonography ...

Introduction: Parathyroid carcinoma (PC) is a rare endocrine malignancy which accounts for 0.005% of all cancers and less than 1% of primary hyperparathyroidism cases. This uncommon tumor usually occurs during the fifth decade of life, with equal frequency in both sexes, and has an indolent but progressive course. It’s frequently symptomatic and patients may have high values of serum calcium and parathyroid hormone (PTH) with a palpable cervical mass. PC generally occurs ...

Introduction: Prolactinomas are the most common hormonally active pituitary tumors that account for 40–60% of all pituitary adenomas and are usually successfully treated with dopamine agonists. Surgery or radiotherapy is reserved for drug intolerance/resistance or in neuro-ophthalmological emergencies. We present a patient with refractory microprolactinoma with empty sella treated by transsphenoidal surgery.Case: 42-year-old female patient admitted ...

Introduction: Hirsutism affects 5–8% of the whole female population. In most patients, hirsutism is associated with hyperandrogenemia and the most common cause of androgen excess is polycystic ovary syndrome; however, the clinical presentation of non-classical congenital adrenal hyperplasia(NCAH) in females is often indistinguishable from other hyperandrogenic disorders because of common clinical signs with hirsutism and poly cystic ovary syndrome(PCOS).<p class="abst...